Bupropion/naltrexone is a combination drug used for weight loss management in obese individuals. It targets multiple pathways in the brain's appetite control and reward systems. Bupropion, an antidepressant, acts as a norepinephrine and dopamine reuptake inhibitor. It helps to reduce appetite and food cravings. Naltrexone, on the other hand, is an opioid receptor antagonist that helps to regulate the reward system associated with food intake. This combination drug is indicated for individuals with a body mass index (BMI) of 30 or higher or a BMI of 27 or higher with comorbidities such as type 2 diabetes or hypertension. It should be used with a reduced-calorie diet and increased physical activity. However, there are specific contraindications to consider. Bupropion/naltrexone should not be used in individuals with uncontrolled hypertension, seizure disorders, or a history of anorexia or bulimia nervosa. It is also contraindicated in those who are taking opioid agonists or are experiencing abrupt opioid withdrawal. Common side effects of bupropion/naltrexone include nausea, headache, constipation, and dizziness. There is also a risk of increased blood pressure and heart rate, which should be monitored regularly during treatment. Learn more about prescription drugs for weight loss and other services we offer: regnerhealthsolutions.com/prescription-drugs/



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